地址：武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话：15172469628
传真：15172469628
邮箱：sales@amyjet.com
Mirus Bio公司是世界上最早开发高效、低细胞毒性转染试剂的公司之一，同时也是目前该类试剂最主要的供应商之一。Mirus Bio的大部分转染试剂可以在含有血清的培养基中进行转染，省去了更换培养基的麻烦。TransIT-L1是Mirus产品的王牌，自1995年开发出来就申请了美国专利(US 5,744,335)。该项专利技术后来License给了Roche公司，以Fugene 6的品牌对外销售。TransIT-TKO & siQUEST转染试剂是常规siRNA转染试剂的王牌，与脂质体介导的转染试剂相比，该转染试剂可以高效转染siRNA，并且极大地降低了细胞的损伤程度。该试剂与siRNA混合转染细胞时，可以特异性剔除某些基因的表达，用于siRNA介导的基因沉默现象的研究。TransIT-Oligo转染试剂是即用型试剂，可以高效地将各种类型的寡聚核苷酸和寡聚脱氧核苷酸转染至受体细胞中。
此外，Mirus Bio还开发了专门针对特殊细胞的体外转染试剂，例如分别针对Jurkat，COS，3T3等细胞的转染试剂。Mirus Bio的科学家们新近开发了一种新的DNA转染试剂：TransITTM-2020 Transfection Reagent。TransITTM的性能优于FuGENETM、LipofectamineTM 2000和 LipofectamineTM 2000 CD；可在多种类型的细胞（包括难转染细胞）中实现高表达。
Mirus was founded on the principle that non-viral (i.e. plasmid DNA based) methods offer distinct advantages over viral methods of gene transfer. Our initial breakthrough in 1996 came with the development of a new type of transfection reagent that combined high efficiency delivery with low cellular toxicity: TransIT®-LT1 (Low Toxicity) Reagent remains the “gold standard” for broad-based gene delivery applications.
Mirus Bio公司主要产品：
Transfection with TransIT
Ingenio® Electroporation
Virus Production
Labeling with Label IT®
In Vivo Delivery
Accessory Products
| 品名 | 货号 |
| Human IgG1 Expression Control – 100 ug | MIR 6250 |
| Ingenio EZporator Electroporation System | MIR 51000 |
| Label IT Nucleic Acid Labeling Kit, Amine – sufficient for modifying 25 µg of nucleic acid | MIR 3925 |
| Label IT Nucleic Acid Labeling Kit, Amine – sufficient for modifying 100 µg of nucleic acid | MIR 3900 |
| TransIT-2020 Transfection Reagent – 0.4 mL | MIR 5404 |
| TransIT-2020 Transfection Reagent – 1.0 mL | MIR 5400 |
| TransIT-2020 Transfection Reagent – 10 X 1.0 mL | MIR 5406 |
| TransIT-2020 Transfection Reagent – 5 X 1.0 mL | MIR 5405 |
| TransIT-293 Transfection Reagent – 0.4 mL | MIR 2704 |
| TransIT-293 Transfection Reagent – 1.0 mL | MIR 2700 |
| TransIT-293 Transfection Reagent – 10 X 1.0 mL | MIR 2706 |
| TransIT-293 Transfection Reagent – 5 X 1.0 mL | MIR 2705 |
| TransIT-CHO Transfection Kit – 10 X 1.0 mL | MIR 2176 |
| TransIT-CHO Transfection Kit – 5 X 1.0 mL | MIR 2175 |
| TransIT-CHO Transfection Kit – 1.0 mL | MIR 2170 |
| TransIT-HeLaMONSTER Transfection Kit – 0.4 mL | MIR 2904 |
| TransIT-HeLaMONSTER Transfection Kit – 1.0 mL | MIR 2900 |
| TransIT-HeLaMONSTER Transfection Kit – 10 X 1.0 mL | MIR 2906 |
| TransIT-HeLaMONSTER Transfection Kit – 5 X 1.0 mL | MIR 2905 |
| TransIT-Insect Transfection Reagent – 0.4 mL | MIR 6104 |
| TransIT-Insect Transfection Reagent – 1.0 mL | MIR 6100 |
| TransIT-Insect Transfection Reagent – 10 X 1.0 mL | MIR 6106 |
| TransIT-Insect Transfection Reagent – 5 X 1.0 mL | MIR 6105 |
| TransIT-Jurkat Transfection Reagent – 0.4 mL | MIR 2124 |
| TransIT-Jurkat Transfection Reagent – 1.0 mL | MIR 2120 |
| TransIT-Jurkat Transfection Reagent – 10 X 1.0 mL | MIR 2126 |
| TransIT-Jurkat Transfection Reagent – 5 X 1.0 mL | MIR 2125 |
| TransIT-Keratinocyte Transfection Reagent – 0.4 mL | MIR 2804 |
| TransIT-Keratinocyte Transfection Reagent – 1.0 mL | MIR 2800 |
| TransIT-Keratinocyte Transfection Reagent – 10 X 1.0 mL | MIR 2806 |
| TransIT-Keratinocyte Transfection Reagent – 5 X 1.0 mL | MIR 2805 |
| TransIT-LT1 Transfection Reagent – 0.4 mL | MIR 2304 |
| TransIT-LT1 Transfection Reagent – 5 X 1.0 mL | MIR 2305 |
| TransIT-mRNA Transfection Kit – 0.4 mL | MIR 2225 |
| TransIT-mRNA Transfection Kit – 1.0 mL | MIR 2250 |
| TransIT-mRNA Transfection Kit – 10 X 1.0 mL | MIR 2256 |
| TransIT-mRNA Transfection Kit – 5 X 1.0 mL | MIR 2255 |
| TransIT-Oligo Transfection Reagent – 0.4 mL | MIR 2164 |
| TransIT-Oligo Transfection Reagent – 1.0 mL | MIR 2160 |
| TransIT-Oligo Transfection Reagent – 10 X 1.0 mL | MIR 2166 |
| TransIT-Oligo Transfection Reagent – 5 X 1.0 mL | MIR 2165 |
| TransIT-PRO Transfection Kit – 1.0 mL (with boost) | MIR 5700 |
| TransIT-PRO Transfection Kit – 10 mL (with boost) | MIR 5760 |
| TransIT-PRO Transfection Reagent – 1 mL (without boost) | MIR 5740 |
| TransIT-PRO Transfection Reagent – 10 mL (without boost) | MIR 5750 |
| TransIT-siQUEST Transfection Reagent – 0.4 mL | MIR 2114 |
| TransIT-siQUEST Transfection Reagent – 1.5 mL | MIR 2110 |
| TransIT-siQUEST Transfection Reagent – 10 X 1.5 mL | MIR 2116 |
| TransIT-siQUEST Transfection Reagent – 5 X 1.5 mL | MIR 2115 |
| TransIT-TKO Transfection Reagent – 0.4 mL | MIR 2154 |
| TransIT-TKO Transfection Reagent – 1.5 mL | MIR 2150 |
| TransIT-TKO Transfection Reagent – 10 X 1.5 mL | MIR 2156 |
| TransIT-TKO Transfection Reagent – 5 X 1.5 mL | MIR 2155 |
| TransIT-X2 Dynamic Delivery System – 0.3 mL | MIR 6003 |
| TransIT-X2 Dynamic Delivery System – 0.75 mL | MIR 6004 |
| TransIT-X2 Dynamic Delivery System – 1.5mL | MIR 6000 |
| TransIT-X2 Dynamic Delivery System – 10 X 1.5 mL | MIR 6006 |
| TransIT-X2 Dynamic Delivery System – 5 X 1.5 mL | MIR 6005 |
| Ingenio Electroporation Accessory – Cell Droppers (50 pk) | MIR 50125 |
| Ingenio Electroporation Solution Only – 25 rxns (6.25 mL) | MIR 50111 |
| Label IT Nucleic Acid Labeling Kit, Biotin – labels 100 µg nucleic acid | MIR 3400 |
| Label IT Plasmid Delivery Control, Cy3 – 10 µg | MIR 7904 |
| Label IT RNAi Delivery Control, Cy3 – 10 µg (0.75 nmol) | MIR 7900 |
| TransduceIT Transduction Reagent – 1 mL | MIR 6620 |
| TransIT-BrCa Reagent Transfection Reagent – 0.4 mL | MIR 5504 |
| Ingenio Electroporation Accessory – 0.4 cm Cuvettes (50 pk) | MIR 50123 |
| Ingenio Electroporation Solution Only – 50 rxns (12.5 mL) | MIR 50114 |
| Label IT Nucleic Acid Labeling Kit, Biotin – labels 25 µg nucleic acid | MIR 3425 |
| Label IT Plasmid Delivery Control, Cy3 – 100 µg | MIR 7905 |
| Label IT RNAi Delivery Control, Cy3 – 100 µg (7.5 nmol) | MIR 7901 |
| Label IT siRNA Tracker Intracellular Localization Kit, CX-Rhodamine – labels 50 µg siRNA | MIR 7214 |
| Label IT Tracker Intracellular Nucleic Acid Localization Kit, CX-Rhodamine – labels 50-200 µg plasmid DNA | MIR 7022 |
| Lentivirus Packaging Mix – 34 rxn | MIR 6640 |
| TransIT-BrCa Reagent Transfection Reagent – 1.0 mL | MIR 5500 |
| TransIT-LT1 Transfection Reagent – 1.0 mL | MIR 2300 |
| Ingenio Electroporation Accessory – 0.2 cm Cuvettes (50 pk) | MIR 50121 |
| Ingenio Electroporation Solution Only – 100 rxns (25 mL) | MIR 50117 |
| Label IT Nucleic Acid Labeling Kit, CX-Rhodamine – labels 100 µg nucleic acid | MIR 3100 |
| Label IT Plasmid Delivery Control, Fluorescein – 10 µg | MIR 7906 |
| Label IT RNAi Delivery Control, Fluorescein – 10 µg (0.75 nmol) | MIR 7902 |
| Label IT siRNA Tracker Intracellular Localization Kit, Cy3 – labels 50 µg siRNA | MIR 7212 |
| Label IT Tracker Intracellular Nucleic Acid Localization Kit, Cy3 – labels 50-200 µg plasmid DNA | MIR 7020 |
| Lentivirus Packaging Mix – 5 rxn | MIR 6630 |
| TransIT-BrCa Transfection Reagent – 5 x 1.0 mL | MIR 5505 |
| Ingenio Electroporation Kit, for Amaxa – 25 rxns (0.2 cm Cuvettes/Droppers) | MIR 50112 |
| Label IT Nucleic Acid Labeling Kit, CX-Rhodamine – labels 25 µg nucleic acid | MIR 3125 |
| Label IT Plasmid Delivery Control, Fluorescein – 100 µg | MIR 7907 |
| Label IT RNAi Delivery Control, Fluorescein – 100 µg (7.5 nmol) | MIR 7903 |
| Label IT siRNA Tracker Intracellular Localization Kit, Cy5 – labels 50 µg siRNA | MIR 7213 |
| Label IT Tracker Intracellular Nucleic Acid Localization Kit, Cy5 – labels 50-200 µg plasmid DNA | MIR 7021 |
| TransIT Lentivirus System – 34 rxn | MIR 6655 |
| TransIT-BrCa Transfection Reagent – 10 x 1.0 mL | MIR 5506 |
| TransIT-LT1 Transfection Reagent – 10 X 1.0 mL | MIR 2306 |
| Ingenio Electroporation Kit, for Amaxa – 50 rxns (0.2 cm Cuvettes/Droppers) | MIR 50115 |
| Label IT Nucleic Acid Labeling Kit, Cy3 – labels 100 µg nucleic acid | MIR 3600 |
| Label IT siRNA Tracker Intracellular Localization Kit, Fluorescein – labels 50 µg siRNA | MIR 7216 |
| Label IT Tracker Intracellular Nucleic Acid Localization Kit, Fluorescein – labels 50-200 µg plasmid DNA | MIR 7025 |
| TransIT Lentivirus System – 5 rxn | MIR 6650 |
| Ingenio Electroporation Kit, for Amaxa – 100 rxns (0.2 cm Cuvette/Droppers) | MIR 50118 |
| Label IT Nucleic Acid Labeling Kit, Cy3 – labels 25 µg nucleic acid | MIR 3625 |
| TransIT-Lenti Transfection Reagent – 10 x 1.5 mL | MIR 6606 |
| Ingenio Electroporation Kit, for other Electroporators – 25 rxns, (0.4 cm Cuvettes/Droppers) | MIR 50113 |
| Label IT Nucleic Acid Labeling Kit, Cy5 – labels 100 µg nucleic acid | MIR 3700 |
| TransIT-Lenti Transfection Reagent – 1.5 mL | MIR 6600 |
| Ingenio Electroporation Kit, for other Electroporators – 50 rxns (0.4 cm Cuvettes/Droppers) | MIR 50116 |
| Label IT Nucleic Acid Labeling Kit, Cy5 – labels 25 µg nucleic acid | MIR 3725 |
| TransIT-Lenti Transfection Reagent – 0.75 mL | MIR 6604 |
| Ingenio Electroporation Kit, for other Electroporators – 100 rxns (0.4 cm Cuvette/Droppers) | MIR 50119 |
| TransIT-Lenti Transfection Reagent – 5 x 1.5 mL | MIR 6605 |
| TransIT-Lenti Transfection Reagent – 0.3 mL | MIR 6603 |
| Label IT Nucleic Acid Labeling Kit, DNP – labels 100 µg nucleic acid | MIR 3800 |
| Label IT Nucleic Acid Labeling Kit, DNP – labels 25 µg nucleic acid | MIR 3825 |
| Label IT Nucleic Acid Labeling Kit, Fluorescein – labels 100 µg nucleic acid | MIR 3200 |
| Label IT Nucleic Acid Labeling Kit, Fluorescein – labels 25 µg nucleic acid | MIR 3225 |
| Label IT Nucleic Acid Labeling Kit, MFP488 – labels 100 µg nucleic acid | MIR 7100 |
| Label IT Nucleic Acid Labeling Kit, MFP488 – labels 25 µg nucleic acid | MIR 7125 |
| TransIT-EE Delivery Solution – 40 Injections | MIR 5340 |
| TransIT-QR Delivery Solution – 40 Injections | MIR 5240 |
| pLIVE Vector – 20 ug | MIR 5420 |
| pLIVE Vector/LacZ – 20 ug of each vector | MIR 5520 |
| pLIVE Vector/SEAP Control Vector Kit – 20 ug of each vector | MIR 5620 |
| pLIVE Vector Complete System – 20 ug of each vector | MIR 5320 |
| RevIT AAV Enhancer – 1.5 mL (for 1 L of cell culture) | MIR 8000 |
| TransIT-VirusGEN GMP Transfection Reagent – 150 mL | MIR 6845-GMP |
| VirusGEN AAV Transfection Kit – 150mL | MIR 6755 |
| VirusGEN AAV Transfection Kit, 1 Kit – for 10 L of cell culture | MIR 6745 |
| RevIT AAV Enhancer – 10 x 1.5 mL (for 10 L of cell culture) | MIR 8006 |
| RevIT AAV Enhancer – 75 mL (for 50 L of cell culture) | MIR 8080 |
| VirusGEN GMP LV Transfection Kit | MIR 6825-GMP |
| VirusGEN LV Transfection Kit | MIR 6760 |
| VirusGEN AAV Kit + RevIT for 10L Culture | MIR 8008 |
| VirusGEN GMP AAV Transfection Kit | MIR 6815-GMP |
| VirusGEN AAV Transfection Kit – 1 Kit for 1 L of cell culture | MIR 6750 |
| VirusGEN AAV Kit + RevIT for 1L Culture | MIR 8007 |
| TransIT-VirusGEN Transfection Reagent – 150 mL | MIR 6740 |
| TransIT-VirusGEN Transfection Reagent – 30 mL | MIR 6720 |
| TransIT-VirusGEN Transfection Reagent – 10 x 1.5 mL | MIR 6706 |
| TransIT-VirusGEN Transfection Reagent – 5 x 1.5 mL | MIR 6705 |
更多详情请联系
艾美捷科技有限公司
全国服务热线：400-6800-868
邮箱：sales@amyjet.com
网站：www.amyjet.com
invivoCrown IV0116替换BioXCell BE0016-2
invivoCrown IV0116替换BioXCell BE0016-2
invivoCrown IV0100替换BioXCell BE0146
艾美捷科技代理Ligatrap品牌全系列产品
LigaTrap Technologies是一家位于北卡罗来纳州的创新型生物技术公司，提供独特的专利技术组合，专注于蛋白质纯化领域。LigaTrap精于抗体与病毒纯化，服务于抗体药物、病毒疫苗及基因治疗产业。
▍LigaTrap公司产品
● LigaGuard：最新推出的亲和吸附剂，是由多模态配体构成的专利复合体系，可在流穿模式（连续流）下选择性捕获宿主细胞蛋白（HCPs）与DNA。
● AAVidity™：一种新型亲和层析填料，用于血清型普适性纯化 源自 HEK293 和 Sf9 细胞裂解液 的 腺相关病毒（AAV）。
● IgM Resin：专为纯化 IgM 抗体设计的亲和树脂，具有高纯度、高结合能力、温和的洗脱条件（pH 约 4.0），并可重复使用多达 100 次。
● Base Resin：专为从多克隆与单克隆来源中纯化高质量抗体而设计，该树脂推荐用于纯化：多种物种的 IgG（包括人、小鼠、兔等）；人源 IgA；鸡源 IgY。
● LigaTrap Buffers：包含Regeneration Buffer，Neutralization Buffer，Elution Buffer，Regeneration Buffer，Equilibration/Wash Buffer 2.0等。
▍LigaGuard
LigaGuard™树脂适用于两类核心产品的纯化：蛋白制品：单克隆抗体、生长因子；病毒制品：慢病毒、腺相关病毒（AAV）、病毒疫苗。该树脂的设计使目标生物产物无结合通过，实现高纯度与高回收率。其能清除传统纯化工艺难以去除的高残留性HCPs（HR-HCPs），显著提升终产物的纯度、稳定性、疗效与安全性。
| 品名 | 货号 | 规格 |
| LigaTrap LigaGuard 1 ml Packed Column | LT-LG1-1x1mL | 1mL |
| LigaTrap LigaGuard 5ml Packed Column | LT-LG1-1x5mL | 5mL |
| LigaTrap LigaGuard Loose Resin - 5mL | LT-LG1 | 5 mL |
| LigaTrap LigaGuard Loose Resin - 10mL | LT-LG1-10mL | 10 mL |
| LigaTrap LigaGuard Loose Resin - 25mL | LT-LG1-25mL | 25 mL |
| LigaTrap LigaGuard Loose Resin - 50mL | LT-LG1-50mL | 50 mL |
| LigaTrap LigaGuard Loose Resin - 100mL | LT-LG1-100mL | 100 mL |
▍AAVidity
AAVidity填料通过合成亲和配体功能化修饰，可捕获所有血清型的 AAV，提供卓越的结合载量与污染物（宿主细胞蛋白 HCPs 及宿主细胞DNA hcDNA清除能力。其温和洗脱条件在保障 AAV 转导活性的同时，实现高产物回收率。
| 品名 | 货号 | 规格 |
| LigaTrap AAVidity Loose Resin – 1mL | LT-AAV-1mL | 1mL |
| LigaTrap AAVidity Loose Resin – 5mL | LT-AAV-5mL | 5mL |
| LigaTrap AAVidity Prepacked Column – 1mL | LT-AAV-1x1mL | 1x1mL |
| LigaTrap AAVidity Prepacked Column – 5mL | LT-AAV-1x5mL | 1x5mL |
▍IgM Resin
IgM纯化树脂的核心优势包括：
● 全面捕获：同时结合IgM的重链与轻链亚型；
● 零风险：无免疫原性及配体脱落；
● 活性保全：温和洗脱条件保障抗体完整性；
● 经济耐用：消毒再生后可重复使用 ≥100 次；
● 该树脂能高效处理并纯化来自以下样本的单克隆 IgM：细胞培养上清，腹水，杂交瘤，其他重组 IgM 来源。
| 品名 | 货号 | 规格 |
| IgM Microspin Column Kit w/ Buffers | LT-155KIT | KIT-10x0.1mL |
| IgM 1mL Prepacked Column Kit w/ Buffers | LT-155-1mL KIT | KIT-1x1mL |
| IgM 5mL Prepacked Column Kit w/ Buffers | LT-155-5mL KIT | KIT-1x5mL |
| IgM Loose Resin – 5mL | LT-155 | 5mL |
| IgM Loose Resin – 10mL | LT-155-10mL | 10mL |
| IgM Loose Resin – 25mL | LT-155-25mL | 25mL |
| IgM Loose Resin – 50mL | LT-155-50mL | 50mL |
| IgM Loose Resin – 100mL | LT-155-100mL | 100mL |
| IgM Microspin Columns without Buffers | LT-155-MSC | 10x0.1mL |
| IgM Prepacked Column – 1mL | LT-155-1x1mL | 1x1mL |
| IgM Prepacked Column – 5mL | LT-155-1x5mL | 1x5mL |
| IgM Prepacked Columns – 3x1mL | LT-155-3x1mL | 3x1mL |
▍Base Resin
LigaTrap基础纯化树脂可实现高回收率与>95%的纯度，而传统Protein A和Protein G填料的回收率甚至低于检测限。通过优化工艺，该树脂的纯度可进一步提升至99%。
| 品名 | 货号 | 规格 |
| Base Resin Microspin Column Kit w/ Buffers | LT-150KIT | KIT-10x0.1mL |
| Base Resin 1mL Prepacked Column Kit w/ Buffers | LT-150-1mL KIT | KIT-1x1mL |
| Base Resin 5mL Prepacked Column Kit w/ Buffers | LT-150-5mL KIT | KIT-1x5mL |
| Loose Base Resin – 5mL | LT-150 | 5mL |
| Loose Base Resin – 10mL | LT-150-10mL | 10mL |
| Loose Base Resin – 25mL | LT-150-25mL | 25mL |
| Loose Base Resin – 50mL | LT-150-50mL | 50mL |
| Loose Base Resin – 100mL | LT-150-100mL | 100mL |
| Base Resin Microspin Columns without Buffers | LT-150-MSC | 10x0.1mL |
| Base Resin Prepacked Column – 1mL | LT-150-1x1mL | 1x1mL |
| Base Resin Prepacked Column – 5mL | LT-150-1x5mL | 1x5mL |
| Base Resin Prepacked Columns – 3x1mL | LT-150-3x1mL | 3x1mL |
▍Buffers
| 品名 | 货号 | 规格 |
| LigaTrap Elution Buffer | BU-123-FP | 125ml |
| LigaTrap Regeneration Buffer | BU-124-FP | 50ml |
| LigaTrap Neutralization Buffer | BU-125-FP | 15ml |
| LigaTrap Storage Buffer | BU-126-FP | 50 ml |
| LigaTrap Sample Diluent 2.0 | BU-131-FP | 15 ml |
| LigaTrap Equilibration/Wash Buffer 2.0 | BU-132-FP | 250ml |
| LigaTrap IgM Elution Buffer pH 3.8 | BU-133-FP | 125 ml |
| LigaTrap Elution Buffer | BU-123-500-FP | 500ml |
| LigaTrap Regeneration Buffer | BU-124-500-FP | 500 ml |
| LigaTrap Neutralization Buffer | BU-125-250-FP | 250 ml |
| LigaTrap Storage Buffer | BU-126-500-FP | 500 ml |
| LigaTrap Sample Diluent 2.0 | BU-131-250-FP | 250 ml |
| LigaTrap Equilibration/Wash Buffer 2.0 | BU-132-1-FP | 1L |
| LigaTrap IgM Elution Buffer pH 3.8 | BU-133-500-FP | 500ml |
invivoCrown IV0110替换BioXCell BE0058
invivoCrown IV0111替换BioXCell BE0036
invivoCrown IV0109替换BioXCell BE0164
艾乐美生物科技有限公司（AllerMAbs Co., Ltd.）成立于2015年，是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体，特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体，将有助于IgE 相关领域的研究工作。因此，AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性，经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠，通过杂交瘤技术 (Hybridoma technology)，成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试，此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性，皆与人类IgE 抗体一致，研究成果于2015 年发表在国际学术期刊上。
AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题，让嵌合人类IgE抗体可以成为人类IgE抗体的替代品，并提供一个更稳定、更符合血清IgE检测系统的校正品，让临床血清IgE的检测结果更加准确与可靠。
其利用动物基因转殖技术，将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes)，分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置，接着把胚胎干细胞分別植入孕母鼠体内，并将其带有嵌入基因之成鼠交互配种，最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice)，且体内能制造完整的嵌合人类IgE抗体分子。
技术优势
容易制备IgE杂交瘤与IgE单抗
过敏原特异性
良好的亲和力与专一性
高纯度与高稳定性
可结合至嗜碱性粒细胞上的IgE受体与刺激細胞
可大量生产与高浓度制备
非人类血液来源(相较于血清IgE抗体)
适合用作检测用的校正品
" data-original="http://genekam.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="AllerMAbs"> AllerMAbs地址：武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话：18372041646
传真：15172469628
邮箱：sales@amyjet.com
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