地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话:18372041646
传真:15172431432
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艾美捷科技代理Medix Biochemica品牌。
Medix Biochemica是重要的体外诊断原材料供应商,生产和供应高质量的抗体、抗原和其他关键的IVD原材料,涵盖免疫测定、临床化学和分子诊断等细分市场。Medix Biochemica拥有5000多种产品,可提供超过95%的最常见试剂,用于检测开发、生产和验证。Medix Biochemica提供高质量的单克隆抗体,也可以提供定制OEM服务,让抗体生产变得轻松。该工艺包括通过细胞系驯化、支原体检测、生产优化和验证进行评估和优化。
Medix Biochemica产品包括:
(1)抗体/抗原/酶:包含5000多种产品,涵盖300多种指标;
(2)MedixMDx:分子生物学应用原料;
(3)生物样本和生物材料。
< " data-original="http://genekam.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理Medix Biochemica品牌"> 艾美捷科技代理Medix Biochemica品牌
美国Plant Cell Technology公司为商业及研究用植物组织培养实验室和植物种植者开发、生产了旗舰产品PPM™ (Plant Preservative Mixture),它是一种广谱抗微生物剂,可以杀死细菌和真菌细胞,防止真菌孢子的萌发,并在较高浓度下能消除内源性污染的外植体。研究表明PPM™活性成分可以渗透过真菌或细菌细胞壁,抑制柠檬酸循环和电子传递链等中心代谢循环中的关键酶的活性,并且可以抑制培养基中的单糖和氨基酸向真菌和细菌细胞的运输。PPM™能有效地抑制植物细胞和植物组织培养中的通过空气、水、人传播的微生物污染及内源性污染,而不会影响体外种子发芽、愈伤组织增殖和愈伤组织的再生。并且,PPM™具有热稳定性,可以和培养基一起灭菌,同时比常用抗生素价更低廉,可以作为植物组织培养基的标准成分。
The principal PCT scientist involved in the development of the PPM™ application is Dr. Assaf Guri. Dr. Assaf Guri holds degrees in genetics, applied genetics and plant breeding from the Hebrew University in Jerusalem and Michigan State University in the US. Before joining Plant Cell Technology, Inc., Dr. Guri worked with the Volcani Agricultural Research Center in Israel, Michigan State University in East Lansing, Michigan and DNAP in New Jersey.
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Kord-Valmark隶属于Bioplast Manufacturing公司,是专业化的培养皿生产商。
Kord-Valmark Labware Products by Bioplast Manufacturing, L.L.C. is a leading manufacturer of quality petri dishes. Our technical knowledge, experience and manufacturing capabilities – along with our superior mold design, precise process control and rigorous quality programs – allow us to manufacture the highest-quality products. Kord-Valmark’s disposable dishes provide unrivaled consistency, ease of use and exceptional value.
Kord-Valmark公司主要产品:
(1)Stackable Petri Dishes
Stackable polystyrene petri dishes are recommended for standard microbiology and general laboratory use
The stackable lid design ensures stability
Optically clear top and bottom viewing surfaces
Consistent flatness allows for even media distribution
Available in 3 sizes: 60 x 15 mm, 100 x 15 mm, and 100 x 25 mm
(2)Automation Petri Dishes
Automation and Slippable polystyrene petri dishes are recommended for standard microbiology and general laboratory use
Slippable lids provide a semi-stacking feature for hand use, while ensuring ease of use in automated equipment
Automation lids have no rim, ensuring ease of use in automated equipment
Select products are available with Side Arrows and/or ISO Mark Targets
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< " data-original="http://genekam.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="KORD-Valmark"> KORD-Valmark
艾美捷科技代理SeraCare对照及参比物质。
艾美捷科技有限公司,自2018年与SeraCare(现隶属于LGC Clinical Diagnostics)合作以来,长期为中国客户提供包括SeraSeq系列参比物质,领域包括肿瘤、生殖健康和遗传病。SeraCare研发和生产一系列临床参比物质,可以用于任何研发阶段,以确保临床基因组学检测结果的准确性。
SeraCare参比物质涵盖的范围:
1)Next Generation Sequencing
2)Sanger Sequencing
3)Real-time PCR and digital PCR (dPCR)
4)Microarray
主要特点
1)Ready-to-use reference materials covering clinically-relevant variants and all variant types - SNVs, INDELS, CNVs, and RNA fusions
2)Highly multiplexed - provide significantly more data per NGS run, saving sequencing costs
3)Available in multiple formats to suite different workflow needs - purified DNA & RNA, ctDNA, encapsulated ctDNA in plasma, and FFPE
4)Manufactured in cGMP-compliant, ISO 13485-certified facilities
5)Stringent product release testing - all variants qualified by dPCR for allele frequencies or copy numbers
| 参比物质 | 货号 | 规格 |
| Seraseq® Whole Transcriptome RNA Seq Mix | 0710-2129 | 1 x 20 µl |
| Seraseq® Unmethylated ctDNA Mutation Mix | 0710-3088 | 1 x 25 µl |
| Seraseq® Tumor Mutation DNA Mix v2 AF 7 HC | 0710-0095 | 1 x 25 µl |
| Seraseq® Tumor Mutation DNA Mix v2 AF 10 HC | 0710-0094 | 1 x 25 µl |
| Seraseq® Tri-Level Tumor Mutation DNA Mix v2 HC | 0710-0097 | 1 x 25 µl |
| Seraseq® TNA (DNA/RNA) WT Mix | 0710-1580 | 2 x 20 µl |
| Seraseq® Solid Tumor CNV Mix, +6 copies | 0710-2867 | 1 x 20 µl |
| Seraseq® Solid Tumor CNV Mix, +3 copies | 0710-2866 | 1 x 20 µl |
| Seraseq® Solid Tumor CNV Mix, +12 copies | 0710-2868 | 1 x 20 µl |
| Seraseq® NTRK Fusion RNA Mix | 0710-1696 | 1 x 20 µl |
| Seraseq® Myeloid Mutation DNA Mix | 0710-0408 | 1 x 25 µl |
| Seraseq® Myeloid Fusion RNA Mix | 0710-0407 | 1 x 25 µl |
| Seraseq Myeloid ctDNA Mix WT | 0710-2646 | 1 x 25 µl |
| Seraseq Myeloid ctDNA Mix AF1% | 0710-2649 | 1 x 25 µl |
| Seraseq Myeloid ctDNA Mix AF0.5% | 0710-2648 | 1 x 25 µl |
| Seraseq Myeloid ctDNA Mix AF0.1% | 0710-2647 | 1 x 25 µl |
| Seraseq® MSI Reference Panel Mix AF5% | 0710-1675 | 2 x 15 µl |
| Seraseq® MSI Reference Panel Mix AF20% | 0710-1676 | 2 x 15 µl |
| Seraseq® Methylated ctDNA Mutation Mix | 0710-3089 | 1 x 25 µl |
| Seraseq® Lymphoma DNA Mutation Mix | 0710-2203 | 1 x 25 µl |
| Seraseq™ Lung & Brain CNV Mix, + 6 copies | 0710-0415 | 1 x 20 µl |
| Seraseq® Lung & Brain CNV Mix, + 3 copies | 0710-0414 | 1 x 20 µl |
| Seraseq® Lung & Brain CNV Mix, + 12 copies | 0710-0416 | 1 x 20 µl |
| Seraseq® HRD gDNA Negative Mix | 0710-2881 | 2 x 20 µl |
| Seraseq® HRD gDNA Low-Positive Mix | 0710-2880 | 2 x 20 µl |
| Seraseq® HRD gDNA High-Positive Mix | 0710-2879 | 2 x 20 µl |
| Seraseq® gDNA TMB Reference Panel Mix | 0710-2463 | 5 x 20 µl |
| Seraseq® gDNA TMB Mix Score 9 | 0710-1325 | 2 x 500 ng |
| Seraseq® gDNA TMB Mix Score 7 | 0710-1326 | 2 x 500 ng |
| Seraseq® gDNA TMB Mix Score 26 | 0710-1323 | 2 x 500 ng |
| Seraseq® gDNA TMB Mix Score 20 | 0710-1324 | 2 x 500 ng |
| Seraseq® gDNA TMB Mix Score 13 | 0710-1586 | 2 x 10 µl |
| Seraseq® gDNA MSI-High Mix | 0710-1670 | 1 x 20 µl |
| Seraseq® gDNA BRCA1/2 LGR Somatic Mutation Mix | 0730-0567 | 1 x 25 µl |
| Seraseq® gDNA BRCA1/2 LGR Inherited Mutation Mix | 0730-0568 | 1 x 25 µl |
| Seraseq® Fusion RNA Mix v4 | 0710-0497 | 1 x 25 µl |
| Seraseq® FFPE WT (DNA/RNA) Reference Material | 0710-0137 | 1 x 10 µm |
| Seraseq® FFPE TMB RM Score 9 | 0710-1308 | 2 x 10 µm |
| Seraseq® FFPE TMB RM Score 7 | 0710-1310 | 2 x 10 µm |
| Seraseq® FFPE TMB RM Score 26 | 0710-1307 | 2 x 10 µm |
| Seraseq® FFPE TMB RM Score 20 | 0710-1309 | 2 x 10 µm |
| Seraseq® FFPE TMB RM Score 13 | 0710-1618 | 2 x 10 um |
| Seraseq® FFPE Solid Tumor CNV Reference Materials | 0710-2865 | 1 x 10 µm |
| Seraseq® FFPE NTRK Fusion RNA Reference Material | 0710-1031 | 1 x 10 µm |
| Seraseq® FFPE MSI-High RM | 0710-2236 | 1 x 10 um |
| Seraseq® FFPE Lymphoma DNA Reference Material | 0710-2202 | 1 x 10 µm |
| Seraseq® FFPE HRD Negative RM | 0710-2644 | 1 x 10 µm |
| Seraseq® FFPE HRD Low-Positive RM | 0710-2645 | 1 x 10 µm |
| Seraseq® FFPE HRD High-Positive RM | 0710-2643 | 1 x 10 µm |
| Seraseq® FFPE Tumor Fusion RNA v4 Reference Material | 0710-0496 | 1 x 10 µm |
| Seraseq® FFPE BRCA1/2 LGR Reference Material | 0730-0564 | 1 x 10 µm |
| Seraseq® ctDNA Reference Material v2 WT | 0710-0208 | 1 x 5 mL |
| Seraseq® ctDNA Reference Material v2 AF2% | 0710-0203 | 1 x 5 mL |
| Seraseq® ctDNA Reference Material v2 AF1% | 0710-0204 | 1 x 5 mL |
| Seraseq® ctDNA Reference Material v2 AF0.5% | 0710-0205 | 1 x 5 mL |
| Seraseq® ctDNA Reference Material v2 AF0.125% | 0710-0207 | 1 x 5 mL |
| Seraseq® ctDNA Mutation Mix v2 WT | 0710-0144 | 1 x 25 µl |
| Seraseq® ctDNA Mutation Mix v2 AF2% | 0710-0139 | 1 x 25 µl |
| Seraseq® ctDNA Mutation Mix v2 AF1% | 0710-0140 | 1 x 25 µl |
| Seraseq® ctDNA Mutation Mix v2 AF0.5% | 0710-0141 | 1 x 25 µl |
| Seraseq® ctDNA Mutation Mix v2 AF0.25% | 0710-0142 | 1 x 25 µl |
| Seraseq® ctDNA Mutation Mix v2 AF0.125% | 0710-0143 | 1 x 25 µl |
| Seraseq® ctDNA MRD Panel Mix | 0710-2146 | 4 x 20 µl |
| Seraseq® ctDNA Complete™ Reference Material WT (0%) | 0710-0674 | 1 x 5 mL |
| Seraseq® ctDNA Complete™ Reference Material AF5% | 0710-0669 | 1 x 5 mL |
| Seraseq® ctDNA Complete™ Reference Material AF2.5% | 0710-0670 | 1 x 5 mL |
| Seraseq® ctDNA Complete™ Reference Material AF1% | 0710-0671 | 1 x 5 mL |
| Seraseq® ctDNA Complete™ Reference Material AF0.5% | 0710-0672 | 1 x 5 mL |
| Seraseq® ctDNA Complete™ Reference Material AF0.1% | 0710-0673 | 1 x 5 mL |
| Seraseq® ctDNA Complete™ Mutation Mix WT (0%) | 0710-0533 | 1 x 25 µl |
| Seraseq® ctDNA Complete™ Mutation Mix AF5% | 0710-0528 | 1 x 25 µl |
| Seraseq® ctDNA Complete™ Mutation Mix AF2.5% | 0710-0529 | 1 x 25 µl |
| Seraseq® ctDNA Complete™ Mutation Mix AF1% | 0710-0530 | 1 x 25 µl |
| Seraseq® ctDNA Complete™ Mutation Mix AF0.5% | 0710-0531 | 1 x 25 µl |
| Seraseq® ctDNA Complete™ Mutation Mix AF0.1% | 0710-0532 | 1 x 25 µl |
| Seraseq® Compromised FFPE WT (DNA/RNA) RM | 0710-1710 | 1 x 10 µm |
| Seraseq® Compromised FFPE Tumor DNA RM | 0710-1492 | 1 x 10 µm |
| Seraseq® Breast CNV Mix, + 6 copies | 0710-0412 | 1 x 20 µl |
| Seraseq® Breast CNV Mix, + 3 copies | 0710-0411 | 1 x 20 µl |
| Seraseq® Breast CNV Mix, + 12 copies | 0710-0413 | 1 x 20 µl |
| Seraseq® Blood TMB Mix Score 7 | 0710-2087 | 3 x 20 µl |
| Seraseq® Blood TMB Mix Score 26 | 0710-2090 | 3 x 20 µl |
| Seraseq® Blood TMB Mix Score 20 | 0710-2089 | 3 x 20 µl |
| Seraseq® Blood TMB Mix Score 13 | 0710-2088 | 3 x 20 µl |
| Seraseq® Turner Syndrome (XO) Reference Material | 0720-0952 | 1 x 1 mL |
| Seraseq® Trisomy 21 Male-Matched Reference Material | 0720-0167 | 1 x 1 mL |
| Seraseq® Trisomy 21 Female-Matched Reference Material | 0720-0168 | 1 x 1 mL |
| Seraseq® Trisomy 18 Male-Matched Reference Material | 0720-0171 | 1 x 1 mL |
| Seraseq® Trisomy 18 Female-Matched Reference Material | 0720-0172 | 1 x 1 mL |
| Seraseq® Trisomy 13 Male-Matched Reference Material | 0720-0779 | 1 x 1 mL |
| Seraseq® Trisomy 13 Female-Matched Reference Material | 0720-0780 | 1 x 1 mL |
| Seraseq® Triple X Syndrome (XXX) Reference Material | 0720-1069 | 1 x 1 mL |
| Seraseq® PGT-A Trisomy 21 Reference Material | 0720-0775 | 1 x 10 µl |
| Seraseq® PGT-A Trisomy 18 Reference Material | 0720-0776 | 1 x 10 µl |
| Seraseq® PGT-A Trisomy 13 Reference Material | 0720-0777 | 1 x 10 µl |
| Seraseq® PGT-A Euploid Reference Material | 0720-0778 | 1 x 10 µl |
| Seraseq® Klinefelter Syndrome (XXY) Reference Material | 0720-0953 | 1 x 1 mL |
| Seraseq® Jacobs Syndrome (XYY) Reference Material | 0720-0954 | 1 x 1 mL |
| Seraseq® Euploid Male-Matched Reference Material | 0720-0169 | 1 x 1 mL |
| Seraseq® Euploid Female-Matched Reference Material | 0720-0170 | 1 x 1 mL |
| Seraseq® 22q11 Male-Matched Reference Material | 0720-0173 | 1 x 1 mL |
| Seraseq® 22q11 Female-Matched Reference Material | 0720-0174 | 1 x 1 mL |
| Seraseq® Inherited Cancer DNA Mix v1 | 0730-0003 | 1 x 200 µL |
| Seraseq® gDNA BRCA1/2 LGR Inherited Mutation Mix | 0730-0568 | 1 x 25 µL |
| Seraseq® FFPE BRCA1/2 LGR Reference Material | 0730-0564 | 1 x 10 µm |
| Seraseq® Cardiomyopathy Reference Material | 0740-0021 | 1 x 200 µL |

艾美捷科技代理Peptides.de品牌全系列产品
Peptides.de是一家专注于高质量肽产品生产的的德国企业。公司创立于2001年,总部位于德国赫尼希斯多夫。从单一肽到百万级肽库,从线性链到环状结构,从短肽到超长序列,从粗品到高纯精肽,从修饰化到标记化,从天然氨基酸到非天然变体,Peptides.de提供全维度肽与肽模拟物解决方案,覆盖新抗原筛选、过继性免疫治疗、T细胞刺激实验、表位作图、ELISpot检测、药物发现及芯片技术等核心领域。
Peptides.de公司不仅生产肽,还自主开发用于肽合成的核心设备——肽合成机器人。凭借其专利技术超声肽合成平台 (USPS®),团队能够在短时间高效生产数百种肽,并精准实现客户所需的各种修饰。

▍ReVacc Scientific公司产品
Peptides.de核心业务涵盖:目录肽现货供应、专属肽链定制合成、个性化肽池构建、高通量肽库开发、肽芯片制备服务、功能型修饰肽生产以及精密预分装服务。

▍Peptides.de部分产品列表
| 品名 | 货号 | 规格 |
| ADV hexon (HLA-B*35:01) | EP07882_1 | 1 mg;5 mg |
| ADV hexon 114 -124 (HLA-B*07:02) | EP07881_1 | 1 mg;5 mg |
| ADV hexon 37-45 (HLA-A*24:02) | EP07880_1 | 1 mg;5 mg |
| ADV hexon 886-894 (HLA-A*01:01) | EP10774_1 | 1 mg;5 mg |
| ADV Hexon 917-925 (HLA-A*02:01) | EP07914_1 | 1 mg;5 mg |
| BKV VP1 108-116 (HLA-A*02:01) | EP11456_1 | 1 mg;5 mg |
| BRLF1 109-117 (HLA-A*02:01) | EP11139_1 | 1 mg;5 mg |
| Chlamydia trachomatis MOMP 258-266 (HLA-A*02:01) | EP11114_1 | 1 mg;5 mg |
| EBNA 3a (596-604) | EP10789_1 | 1 mg;5 mg |
| EBNA-1 Protein (562-570) | EP04510_1 | 1 mg;5 mg |
| EBV BALF-4 276-284 (HLA-A*02:01) | EP11237_1 | 1 mg;5 mg |
| EBV BMLF-1 280-288 (HLA-A*02:01) | EP07604_1 | 1 mg;5 mg |
| EBV BMRF1 116-128 (HLA-B*07:02) | EP11138_1 | 1 mg;5 mg |
| EBV BMRF1 208-216 (HLA-A*02:01) | EP11127_1 | 1 mg;5 mg |
| EBV BRLF-1 148-156 (HLA-A*03:01) | EP11482_1 | 1 mg;5 mg |
| EBV BRLF1 101-109 (HLA-A*29:02) | EP11142_1 | 1 mg;5 mg |
| EBV BRLF1 134-142 (HLA-A*11:01) | EP11140_1 | 1 mg;5 mg |
| EBV BRLF1 28-37 (HLA-A*24:02) | EP11141_1 | 1 mg;5 mg |
| EBV BZLF-1 190-197 (HLA-B*08:01) | EP07899_1 | 1 mg;5 mg |
| EBV BZLF-1 54-64 (HLA-B*35:01) | EP11143_1 | 1 mg;5 mg |
| EBV BZLF-1 54-64 mutant (HLA-B*35:01) | EP11144_1 | 1 mg;5 mg |
| EBV BZLF1 44-52 (HLA-B*07:02) | EP11214_1 | 1 mg;5 mg |
| EBV EBNA 3A 246-253 (HLA-A*24:02) | EP11147_1 | 1 mg;5 mg |
| EBV EBNA 3B 399-408 (HLA-A*11:01) | EP11150_1 | 1 mg;5 mg |

PhytoTechnology(简称PhytoTech)公司是一家专门从事于研发和生产植物组织培养基,植物学技术相关产品的一家科研生产性企业。由Dr. Kenneth C. Torres博士和他的妻子Janet 于1997年在美国Lenexa, Kansas州创立,随着公司产品的不断改进和更新,目前PhytoTech公司已经成为了世界上著名的植物生物学类产品的生厂商和原料供应商,其公司产品以稳定的质量和优质的价格已赢得了世界范围内众多客户的认可,并在植物学的各个领域内广泛使用。
PhytoTechnology Laboratories manufactures and distributes products to the plant tissue culture, plant biotechnology, and plant science markets. Our products are used to mass propagate plants on sterile culture media in laboratory settings. We also supply products for the genetic improvement of plants through gene transformation research. Manufacturing, product development, administration and distribution of products are all performed at the PhytoTechnology Laboratories campus (20,000 square feet of production and research and development space) in Overland Park, a suburb of the Kansas City metro area in Kansas. This central US location provides direct access to most major markets around the world.
PhytoTechnology公司主要产品包括:
Plant Media
Biochemicals
Molecular Biology
Microbiology
Phytopathology
Phycology
Seed Testing
Kits Equipment
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Lunginnov公司位于法国里尔市,主要产品线包括生命科学试剂和体外诊断医疗器械。Lunginnov公司最大的特色是为研究者提供Endocan和CG-Cleaved Endocan检测产品(包括抗体、ELISA试剂盒、重组蛋白等),这两个分子已经被证明是肺部感染/损伤的标志分子。
Lunginnov develops innovative solutions for respiratory diseases that enable earlier therapeutic decision to be helpful for patients. Lunginnov markets 2 product lines:
A range of unique reagents for research in Life Sciences
A range of original medical devices for In Vitro Diagnostic
Lunginnov is declared manufacturer to the french regulatory agency ANSM. The company devotes a significant part of its budget to its internal R&D and to set up collaborative projects with Research Centers in France and abroad. Lunginnov is specialized on endocan and CG-cleaved endocan as markers of lung infection/injury, by proposing specific tools of high quality researchers and clinicians.
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邮箱:sales@amyjet.com
网站:www.amyjet.com

Diarect有着20多年自身抗原研发经验的Liedvogel教授和Hanbruck博士联手创建。1993年Haubruck博士利用杆状病毒/Sf9昆虫细胞表达系统成功的研发出人重组抗原--TPO,6年后Diarect是第一家将人重组TPO引进体外诊断市场的公司。
Established in 1998, DIARECT AG is a privately owned biotech company with expertise in developing and establishing standardized large-scale productions of both recombinant and native proteins, including their worldwide distribution. Providing customers with products and services of consistent quality is one of the cornerstones of DIARECT’s business philosophy.
DIARECT is not only a leading manufacturer of autoimmune and infectious disease antigens, but also of recombinant allergens. In additon, DIARECT is the exclusive distributor of Surmodics in Europe. With Surmodics' protein stabilization reagents, blockers and BioFX substrates, DIARECT is able to provide most of the critical components for the development of diagnostic end products.
Diarect公司的主要产品包括:
Allergens
Autoimmune Disease Antigens
Infectious Disease Antigens
Antigen FAQ
Selected References
Protein Stabilizers / Blockers
Immunoassay Stabilizers
Protein and Conjugate Stabilizers
Microsphere and Microarray Stabilizers
StabilBlot™ Blockers
Protein Stabilizers / Blockers FAQ
Selected References
Immunoassay Substrates
<更多详情请联系
艾美捷科技有限公司
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邮箱:sales@amyjet.com
网站:www.amyjet.com
< " data-original="http://genekam.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="Diarect"> Diarect
艾美捷科技代理Gene Tools品牌
Gene Tools是一家生产和销售Morpholino Anti-sense oligos(反义寡核苷酸)的公司,其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成,为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具,已被广泛用于:阻断靶mRNA 翻译 (下调基因);诱导RNA选择性剪接 (下调或上调基因);阻断 miRNA;阻断病毒 RNA;阻断 non-coding RNA。
▍Morpholino介绍
Morpholino属于第三代反义寡核苷酸,主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用,目前已经广泛用于发育生物学和细胞学实验中,并取得了非常好的实验效果。
Morpholino以吗啉环类似物为基本骨架,这种独特的结构特性使得Morpholino 具有以下几个特点:
● 与其他类型的反义寡核苷酸相比,Morpholino 能更好地抵抗核酸酶的作用;
● Morpholino 与靶序列结合后通过空间位阻效应发挥作用, 不激活RNaseH,不引起目标基因mRNA 的降解 ;
● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译,针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切,得到不 同的转录本,可以方便地用于目标基因结构域的突变研究;
● 与靶序列结合能力强,可以渗入mRNA 的二级结构, 并且特异性好。
配合Morpholino 的使用,Gene Tools公司开发了相应的递送系统,可以安全、高效地将Morpholino 输送至胞内,因此,Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外,Morpholino 可以标上荧光基团、亲和标签以及活性反应基团,以供不同的研究需要。

▍Gene Tools公司产品介绍
● Custom Morpholino:可以根据目标基因序列定制设计并合成Morpholino,用于体外细胞实验或某些直接显微注射的模型(如斑马鱼、非洲爪蟾胚胎)。
● Vivo-Morpholino:适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。通过特殊的末端修饰,提高了其穿透细胞膜进入组织细胞的能力,使得在成年动物(主要是小鼠、大鼠)中进行系统性基因功能研究成为可能。
● Prepared Control Oligos:根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。
| 产品名称 | Short Description | Oligo sequence | SKU |
| Standard Control Oligo | Negative control oligo | CCTCTTACCTCAGTTACAATTTATA | PCO-StandardControl-100 |
| Vivo-Morpholino Standard Control Oligo | Negative Vivo-Morpholino control oligo | CCTCTTACCTCAGTTACAATTTATA | PCO-VivoStandardControl-100 |
| Random Control Oligo 25-N | 25-base random sequence mixture | NNNNNNNNNNNNNNNNNNNNNNNNN | PCO-RandomControl-25N-100 |
| Zebrafish p53 oligo | Danio rerio apoptosis suppression oligo | GCGCCATTGCTTTGCAAGAATTG | PCO-ZebrafishP53-100 |
| Zebrafish Chordin Positive Control Oligo | Danio rerio Chordin positive control oligo | ATCCACAGCAGCCCCTCCATCATCC | PCO-ZebrafishChordin-100-F |
| Clawed Frog Beta Catenin Positive Control Oligo | Xenopus laevis Beta Catenin antisense oligo | TTTCAACCGTTTCCAAAGAACCAGG | PCO-BetaCatenin-100-F |
| Green Fluorescent Protein Positive Control | Translation blocker for GFP target | ACAGCTCCTCGCCCTTGCTCACCAT | PCO-GFPControl-100 |
| Vivo-Morpholino GFP Positive Control | Translation blocker for GFP target (Vivo-Morpholino) | ACAGCTCCTCGCCCTTGCTCACCAT | PCO-VivoGFPControl-100 |
| Fluoresceinated Vivo-Morpholino Std Control | Negative Vivo-Morpholino control oligo with 5'Fluorescein | CCTCTTACCTCAGTTACAATTTATA | PCO-FluorVivoStandardControl-100-F |
● Endo-Porter:为了解决Morpholino在体外培养细胞中摄取效率低的问题,Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。

SERO生产以下系列专利产品Seronorm™, Pathonorm™ and Autonorm™。除此之外,也为客户提供个性化定制产品。
Seronorm™系列
主要产品包括免疫对照,结合激素,心脏和肿瘤标志物,Seronorm™所有对照血清来源为人,不含防腐剂和稳定剂,产品文档全面,为市场上最常用的仪器提供超过50种分析物的分配值,可提供四个不同临床级别,且每一级别都可单独提供。Seronorm™ Immunoassay Liq low – 含有与临床相当的低水平的醛固酮,雄烯二酮,皮质醇,铁蛋白,IgE,17-OH-孕酮,PSA总量,睾酮,游离T4,TSH,25-OH-维生素D和维生素B12
Pathonorm™ and Autonorm™
Pathonorm™临床化学级对照,不含防腐剂和稳定剂的动物血清,适合大部分临床化学分析,为市面上常用仪器提供超过38种分析物的分配值,有两种临床级别,且都可以单独提供,产品以冻干粉形式提供,货架期长。
Autonorm™
满足绝大部分临床化学实验室正常水平的分析级的高品质对照,不含防腐剂和稳定剂的动物血清,不含Pharmaca。文档齐全,为市场上最常用的仪器提供超过30种分析物的分配值,冻干粉,货架期长。
客户定制产品:
SERO也针对有质量意识的诊断公司,组织提供定制服务,SERO可定制的高品质对照产品如下:
常规血清化学(人或动物基质)
常规尿液化学
脂质
激素
肿瘤标记
心脏标志物
蛋白质
治疗药物
专业和护理点控制(CRP,HbA1C,血红蛋白,葡萄糖)
微量元素和重金属
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